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Mycoplasma hominis

Mycoplasma hominis

Conditions

Mycoplasma hominis — conditionally pathogenic urogenital bacterium. PCR diagnostics and treatment.

What is Mycoplasma hominis?

Mycoplasma hominis is a cell wall-deficient bacterium that can colonize the urogenital tract. It is a conditionally pathogenic organism — present in healthy individuals but causing infection under certain conditions.

Infection symptoms

  • Often asymptomatic — part of normal microflora in 10-30% of women
  • Bacterial vaginosis — elevated pH, fishy odor, gray-white discharge
  • PID — lower abdominal pain, fever, abnormal bleeding
  • Postpartum fever — infection after delivery
  • Urinary tract infections — dysuria, frequent urination

Reproductive significance

  • Infertility — associated with tubal inflammation
  • Preterm birth — associated with premature rupture of membranes
  • Neonatal infections — meningitis, pneumonia in newborns

Diagnostics

  • PCR test — most precise detection and quantification method
  • Culture — specific mycoplasma culture
  • Cervical swab or urine for analysis

Treatment

Mycoplasma hominis is treated with macrolide or tetracycline antibiotics (azithromycin, doxycycline). Treatment is recommended when symptoms are present or when planning pregnancy.

Dr Slobodanka Petković

Written by

Dr Slobodanka Petković

Specialist in Gynaecology & Obstetrics · 35+ years of experience

Last updated: April 2026

Patients often ask

No. Mycoplasma hominis is part of normal flora in many women. Treatment is needed only if causing symptoms or when planning pregnancy.

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